(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one
MAREIN
CAS: 535-96-6
Molecular Formula: C21H22O11
(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one - Names and Identifiers
| Name | MAREIN |
| Synonyms | MAREIN MAREIN hplc MAREIN WITH HPLC OKANIN-4'-O-GLUCOSIDE Okaini 4'-O-β-D-glucopyranoside 2',3,3',4,4'-PENTAHYDROXY-4'-GLUCOSYLCHALCONE (E)-4'-(β-D-Glucopyranosyloxy)-2',3,3',4-tetrahydroxychalcone (E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one |
| CAS | 535-96-6 |
| EINECS | 208-623-1 |
(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one - Physico-chemical Properties
| Molecular Formula | C21H22O11 |
| Molar Mass | 450.39 |
| Density | 1.664±0.06 g/cm3(Predicted) |
| Melting Point | 197-202°C |
| Boling Point | 835.4±65.0 °C(Predicted) |
| Appearance | Yellow powder |
| pKa | 6.92±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD00017496 |
(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one - Risk and Safety
| Hazard Symbols | Xi - Irritant |
(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one - Reference
| Reference Show more | 1. Zhuoicing rain, Wei Shengli, Feng Lagerstroemia, Shi Yan, Ren mi-mi, Zhao Ting, Zhang Yuan. Comparative study on the quality of snow chrysanthemum and its variation types [J]. Journal of Beijing University of Chinese Medicine, 2021,44(01):69-77. 2. Liu Jing et al. [IF = 2.63]. "Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach. 2022;2022:6707811 |
(E)-3-(3,4-dihydroxyphenyl)-1-[4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl]-2-propen-1-one - Reference Information
| biological activity | Marein has a neuroprotective effect by reducing the damage to mitochondrial function and the activation of AMPK signaling pathway. Marein promotes glucose uptake through CaMKK/AMPK/GLUT1, increases glycogen synthesis through IRS/Akt/GSK-3β, and reduces Gluconeogenesis through Akt/FoxO1, thereby improving high glucose-induced insulin resistance in HepG2 cells. Marein is an HDAC inhibitor with an IC50 of 100 μm. Marein has beneficial antioxidant, antihypertensive, hypolipidemic and antidiabetic effects. |
| Target | IC50: 100 µm (HDAC) |
Last Update：2024-04-09 20:13:35
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Spot supply
Product Name: MAREIN Visit Supplier Webpage Request for quotationCAS: 535-96-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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